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Valproic acid
CAS No. 99-66-1
Valproic acid ( VPA;2-Propylpentanoic Acid )
Catalog No. M16914 CAS No. 99-66-1
A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 45 | In Stock |
|
Biological Information
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Product NameValproic acid
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NoteResearch use only, not for human use.
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Brief DescriptionA HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
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DescriptionA HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2; induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients; reduces tumor growth and metastasis formation in animal model.Migraine Approved
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SynonymsVPA;2-Propylpentanoic Acid
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorGABA; Sodium Channel; HDACs
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Research AreaNeurological Disease
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IndicationMigraine
Chemical Information
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CAS Number99-66-1
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Formula Weight144.21
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Molecular FormulaC8H16O2
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Purity>98% (HPLC)
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Solubility10 mM in H2O
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SMILESCCCC(CCC)C(O)=O
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Chemical NamePentanoic acid, 2-propyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Krmer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
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